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Cold Plasma Market: Growth, Size, Share, and Trends

Report Code MD 5001
Published in Jan, 2025, By MarketsandMarkets™
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Cold Plasma Market by Industry (Textile, Electronics & Semiconductors, Polymer & Plastic, Food & Agriculture, Medical, Cosmetic), Application (surface treatment & activation, wound Healing), Regime (Atmospheric, Low Pressure) - Global Forecast to 2029

Updated on : January 24, 2025

Overview

The global cold plasma market, valued at US$2.01 billion in 2023, is forecasted to grow at a robust CAGR of 11.0%, reaching US$2.17 billion in 2024 and an impressive US$3.66 billion by 2029. The surge in applications of cold plasma, the launch and approval of advanced products, and favorable developments in government policies to promote low-cost devices will stimulate market growth. Much of the demand for cold plasma is due to increased applications & benefits, increasing cases of cancer and chronic wounds, and a large patient pool requiring cold plasma products for wound healing and cancer treatment. Moreover, the increased focus on sustainability and ecofriendly technologies and growing awareness in emerging economies will further support the growth of the cold plasma market in the coming years.

Cold Plasma Market– Global Forecast and Key Opportunities to 2029

Attractive Opportunities in the Cold Plasma Market

North America

Market growth in North America can be attributed to increased R&D investments, the growing prevalence of chronic diseases, and the large presence of well-established companies.

The cold plasma market is driven by the growing prevalence of cancer and chronic wounds, technological advancements, a surge in product launches, and wider industrial applications.

Increased benefits of cold plasma over conventional methods, the growing inclination toward sustainability and ecofriendly technologies, and an increased focus on advanced cold plasma products will likely promote significant growth opportunities in the market.

North America dominates the cold plasma market. It is projected to reach USD 1.49 billion by 2029, at a CAGR of 10.5%.

Asia Pacific is the fastest-growing market for cold plasma, with China and India emerging as major growth hotspots.

Global Cold Plasma Market Dynamics

DRIVER: Increasing use of cold plasma in wound healing

Advances in cold plasma technology have shown promise in treating chronic wounds, particularly those related to diabetes, which affects 1–2% of the population in developed nations. These wounds take a long time to heal and are costly to treat. Cold atmospheric plasmas offer a painless and safe way to reduce bacterial infections, including multidrug-resistant strains, and promote healing. With the rising incidence of diabetes and obesity, untreated wounds can lead to pain, discomfort, mental stress, and financial burdens. Cold atmospheric plasmas also show potential for treating burn wounds by inhibiting bacteria and promoting tissue regeneration. They may become a standard part of burn care in the near future.

On the other hand, road traffic accidents remain one of the leading causes of trauma, and utilization of cold plasma in hospitals and healthcare organizations is likely to increase. With more than 21 million seniors projected to live in Germany by 2040 (Germany Federal Statistical Office, 2020), the demand for the development of effective wound management solutions will increase with this population. Among the numerous treatment modalities developed and available, cold plasma represents one of the most promising options for chronic wounds.

RESTRAINT: High capital investments

One of the main barriers to the adoption of cold plasma technology, particularly for small businesses and start-ups, is the high capital intake in the early stages. While some of this equipment (including installation and subsequent maintenance) can cost between USD 0.55 million and 1.10 million (EUR 0.5 million and 1 million), few potential users see this as a justification for such expenditure. This cost may discourage companies from investing if they are unsure of the high returns on investment, hence opting for more longstanding and cheaper alternatives.

Apart from the aforementioned costs, the processes of cold plasma are inherently complicated. This technology demands a highly specialized workforce to handle and maintain the systems, thus increasing the overall cost. Moreover, the coating process varies widely with application, industry, and material and necessitates largely customized procedures and specialized equipment, which increases capital investments. Professional-grade cold plasma machines range from USD 3,499 to over USD 5,000, depending on features and capabilities. The price is much higher for most applications, such as wound care for example, or in treatments with oncology.

This heavy cost and need for specialized training motivate many industries to adopt alternative technologies for coating and treatment applications, which further impedes the widespread adaptation of cold plasma solutions.

 

OPPORTUNITY: Untapped growth potential in emerging markets

Emerging markets, especially those of the Asia Pacific and Latin America, like India, China, and Brazil, offer opportunities for the growth of cold plasma technology. Less stringent regulations, cost advantages, and the availability of inexpensive labor and raw materials are further driving ongoing industrialization in such markets. In the treatment of bacterial and viral diseases, the Asia Pacific region would grow the highest due to the increased adoption of advanced technologies.

Rising income levels and an increase in population are further expanding the cold plasma market across various industries, including textiles, food & beverage, semiconductors, electronics, plastics, and medical devices. For example, the per capita disposable income in India rose by 8% in FY24, indicating a positive economic climate for manufacturing as well as private investment (Source: Bureau).

Considering Asia accommodates more than half of the global population, cold plasma technologies can significantly impact its ability to modernize wound care, sterilization, and infection control—especially with the aging population on the rise. China's population aged 60 and older will cross 300 million by 2024. Governments in the region are promoting private investments in health and agriculture, thus developing public-private partnerships that will further improve access for industries. Furthermore, growing investments and facilitatory regulatory policies support and make emerging Asian economies conducive to the cold plasma market.

Additionally, international corporations are expanding their research & development and distribution capabilities in the region. For instance, in 2021, Adtec Plasma Technology Co., Ltd. (Japan) launched a series of plasma generators, solidifying its position in the market. Collectively, these factors are expected to create numerous opportunities for the cold plasma market in emerging economies.

CHALLENGES: Low commercialization and awareness of cold plasma

The cold plasma market is currently dominated by only a few small players, and commercialization of this technology has been limited over the past decade. Its successful applications have been confined to a few sectors due to the low number of production units for cold plasma-related products worldwide. Although cold plasma technology has great potential in dental and medical treatments, its adoption is hindered by high treatment costs and limited general awareness. Many potential users are unaware of its benefits, such as improved wound care, sterilization, and pest control. Another challenge is the lack of trained personnel to operate and use cold plasma technologies, particularly in the healthcare and agricultural sectors. This lack of expertise can lead to inefficiencies and hinder adoption.

To address these challenges, it is essential to invest in training programs with academic institutions to develop specialized curricula. This will help create a skilled workforce that can drive innovation and broader adoption of cold plasma solutions. Therefore, limited commercialization, lack of skilled professionals, and low awareness represent significant challenges to the market's growth.

Global Cold Plasma Market Ecosystem Analysis

The cold plasma market encompasses a complex system involving different types of players, such as manufacturers, and industries like textile, food processing, and electronics. There are significant applications for cold plasma technology in medicine, such as healing wounds and sterilization. It is also used for industrial surface treatments, coating, and printing. Regulatory agencies ensure that customers have access to safe systems. Support services focus on providing technical support to customers. Ongoing research and development, as well as increased investments, are driving technological advancements and expanding the market for cold plasma technology. This is expected to lead to increased usage of cold plasma technology across various industries in the coming years.

Cold Plasma Market Ecosystem
 

By industry, the polymer & plastic industry is expected to be the largest segment during the forecast period

In 2023, the polymer & plastic industry segment held the largest share of the cold plasma market. The plasma treatment of polymers is gaining popularity as a surface modification technique because this technique does not require any water or chemicals. Thus, it can be considered an environment-friendly technology. This technique is versatile because it affects only a few atomic layers at the surface without affecting the bulk properties of polymers. Some of the gases or mixtures of gases used in the treatment of polymers with cold plasma include air, nitrogen, argon, oxygen, nitrous oxide, helium, tetrafluoromethane, water vapor, carbon dioxide, methane, and ammonia. Each produces a different composition of plasma and, consequently, different properties on the polymer surface.

The US plastic industry's export markets grew by 22.6% in 2021. The industry's trade deficit increased to USD 10.1 billion in 2021 from USD 5.4 billion the previous year, indicating that the country imported more plastic products than it exported. The rising trade deficit in plastics presents an opportunity for cold plasma market players to help US manufacturers overcome challenges and achieve a better competitive stance in the globalized economy (Source: Plastics Industry Association).

Improved wettability, induced chemical reactivity, enhanced adhesion to coatings and matrices, better hydrophobic properties, and easier cleaning or disinfection are the main driving forces behind the adoption of cold plasma techniques in the polymer & plastic industry. These factors are driving the growth of the cold plasma market for the polymer & plastic industry.

By application, surface treatment & activation applications are expected to be the fastest-growing segment during the forecast period

In 2023, the market for cold plasma was dominated by the surface treatment & activation application segment. The adhesion of coatings onto polymer surfaces or the bonding of polymers is a chronic and challenging problem in the plastic industry. Some properties of polymers that make it difficult to apply a coating are chemical inertness/solvent sensitivity, the presence of antioxidants, plasticizers, antistatic effects, temperature sensitivity, and low surface tension. Plastics are composed of non-polar, long-chain molecules and have minimal free surface energy, making them inert.

The process of cold plasma treatment helps change the chemical characteristics of polymers and plastics so that they can adhere better to the applied coating. It is this aspect that provides better wetting, short-term adhesion, and stability. In addition, surface activation improves the surface energy of the material, which increases its ability to engage with adhesives, inks, or coatings. This is useful for both polymers and metals.

The plastics industry is flourishing and offers exciting business opportunities for cold plasma technology. For instance, in May 2024, manufacturing of plastic products rose for the fourth consecutive month, showing a strong rebound and further gains in sentiment for the sector. This steady growth reflects the growth in demand for plastics. The estimated demand for US plastics in May 2024 was USD 22.8 billion, which was a 1.4% increase from April 2024 and a 3.5% increase from May 2023. This growth represents the highest demand increase since January 2024 (Source: Plastics Engineering).

By region, North America will continue to be dominant during the forecast period

North America, comprising the US and Canada, is projected to be the largest market for cold plasma during the forecast period. The market is driven by the growing incidence of foodborne diseases, government initiatives, increasing R&D funding, and increasing focus on the application of novel techniques in the medical, semiconductors & electronics, food & agriculture, and textile industries.

The US market has a high degree of regulation regarding non-toxic and non-volatile organic compounds (VOCs). In the US, regulations are controlled by the Environmental Protection Agency (EPA), which, in recent years, has been striving to shift focus towards the use of compact decontamination devices and eco-friendly products and technologies. The use of cold plasma has become more prevalent compared to traditional sources, especially in the medical and food & beverage sectors in North America. Market growth in the food & beverage sector is driven by factors such as the need for a longer shelf life, evolving food processing requirements, and favorable food preservation regulations.

Moreover, in the last couple of years, North America's food safety regulatory bodies have approved a number of cold plasma technologies used in food processing because this technique is very effective and has minimal negative effects on the nutritional and textural properties of products.

The North American market for cold plasma-processed food & beverage products is driven by the demand for health and wellness products. Companies in this market are investing in research and development to innovate functional products. Economic downturns have caused changes in consumer behavior, leading companies to lower prices to maintain sales volumes. As a result, companies are now required to design new technologies that can help develop new functional products at lower costs. This factor has contributed to the growth of cold plasma in various industries.

Key players in this region include Nordson Corporation (US), Apyx Medical (US), Enercon Industries Corporation (US), Surfx Technologies, LLC (US), and Thierry Corp. (US).

HIGHEST CAGR MARKET IN 2023
US FASTEST GROWING MARKET IN THE REGION
Cold Plasma Market Region

Recent Developments of Cold Plasma Market

  • In January 2025, Plasmatreat GmbH (Germany) launched PFW10LT Openair-Plasma nozzle, a low-temperature nozzle that activates thermally sensitive materials and surfaces with high intensity.
  • In January 2025, Plasmatreat GmbH (Germany) launched PFW100 Openair-Plasma nozzle, that treats flat components or surfaces at high process speeds and at the same time over a large width.
  • In December 2024, Relyon plasma GmbH (Germany) collaborated with Viromed Medical GmbH (Germany) to drive research on the use of cold atmospheric pressure plasma in medicine. Relyon plasma is responsible for developing the technology that utilizes plasma and Viromed is responsible for the approval of the device and its distribution.
  • In December 2024, Plasmatreat GmbH (Germany) opened a new sales office in the Czech Republic. This strategic movement helped the company to take a further step towards strengthening its proximity to customers in the Czech Republic and Slovakia and further intensifying cooperation.

Key Market Players

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Scope of the Report

Report Metric Details
Market size available for years 2024-2029
Base Year Considered 2023
Forecast period 2024-2029
Forecast units Value (USD Million/Billion)
Segments covered Industry, Application, Regime, and Region
Geographies covered North America (US & Canada), Europe (Germany, the UK, France, Italy, Spain, and RoE), APAC (Japan, China, Australia, South Korea India, and the RoAPAC), LATAM (Brazil, Mexico, and RoLATAM), and MEA (GCC Countries, RoMEA)

 

Key Questions Addressed by the Report

What are the key drivers for the cold plasma market?
The market for cold plasma is driven by the increasing demand for advanced medical treatments and wider industrial applications. Advancements in technology and sustainability regulations, as well as growth in the electronics industry and increased R&D investments, are pushing the adoption of cold plasma technology across various end-user industries. These factors are expected to propel the market during the forecast period.
Which application segment in the cold plasma market provides the most opportunity for growth?
The surface treatment & activation application segment is poised for growth in the cold plasma market due to its ability to enhance adhesion and modify surface properties without damaging substrates. As industries prioritize efficient, eco-friendly solutions and sustainable practices, the versatility of cold plasma technology is increasingly recognized in sectors like electronics, automotive, and medical devices.
Which regime segment provides the most opportunity for growth?
The low atmospheric plasma regime segment is poised for growth in the cold plasma market due to its ability to operate effectively under ambient conditions. This makes it suitable for a wide range of applications without the need for vacuum systems. Its versatility in improving surface properties and facilitating processes like sterilization and coating drives adoption across industries such as healthcare, electronics, and packaging.
What are the main vendors present in this market?
The main vendors in the market are Apyx Medical (US), Nordson Corporation (US), Adtec Plasma Technology Co. Ltd. (Japan), P2i Ltd. (UK), Relyon Plasma GmbH (Germany), Henniker Plasma (UK), Enercon Industries Corporation (US), AcXys Plasma Technologies (France), Plasmatreat GmbH (Germany), and Tantec A/S (Denmark).
Which region is expected to witness the highest demand growth for cold plasma in the coming years?
The Asia Pacific region is poised for significant growth in the cold plasma market due to rapid industrialization, increasing disposable incomes, and a rising focus on advanced technologies in sectors like healthcare, food processing, and textiles. Government support for R&D initiatives and favorable regulatory environments further enhance investment opportunities, driving the adoption of cold plasma solutions across diverse industries.

 

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This study involved the extensive use of both primary and secondary sources. The research process involved the study of various factors affecting the industry to identify the segmentation types, industry trends, key players, competitive landscape, fundamental market dynamics, and key player strategies.

Secondary Research

The secondary research process involves the widespread use of secondary sources, directories, databases (such as Bloomberg Businessweek, Factiva, and D&B Hoovers), white papers, annual reports, company house documents, investor presentations, SEC filings of companies and publications from government sources [such as National Institutes of Health (NIH), US FDA, US Census Bureau, World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), Plasma Protein Therapeutic Association (PPTA), International Diabetes Federation (IDF),European Textile Services Association (ETSA), National Council of Textile Organizations (NCTO), Semiconductor Industry Association (SIA), International Journal of Plastic and Polymer Technology (IJPPT), International Journal of Engineering Research & Technology (IJERT and Centers for Medicare and Medicaid Services (CMS) were referred to identify and collect information for the global cold plasma market study. It was also used to obtain important information about the key players and market classification & segmentation according to industry trends to the bottom-most level and key developments related to market and technology perspectives. A database of the key industry leaders was also prepared using secondary research.

Primary Research

In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include industry experts such as CEOs, vice presidents, marketing and sales directors, technology & innovation directors, and related key executives from various key companies and organizations in the cold plasma market. The primary sources from the demand side include hospitals & clinics, physiotherapy clinics and home care settings. Primary research was conducted to validate the market segmentation, identify key players in the market, and gather insights on key industry trends & key market dynamics.

A breakdown of the primary respondents is provided below:

*C-level primaries include CEOs, CFOs, COOs, and VPs.

*Others include sales managers, marketing managers, business development managers, product managers, distributors, and suppliers.

Note: Companies are classified into tiers based on their total revenue. As of 2023, Tier 1 = >USD 10.00 billion, Tier 2 = USD 1.00 billion to USD 10.00 billion, and Tier 3 = < USD 1.00 billion.

Source: MarketsandMarkets Analysis

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Market Size Estimation

For the global market value, annual revenues were calculated based on the revenue mapping of major product manufacturers and OEMs active in the global cold plasma market. All the major product manufacturers were identified at the global and/or country/regional level. Revenue mapping for the respective business segments/sub-segments was done for the major players (who contribute at least 70-75% of the market share at the global level). Also, the global cold plasma market was split into various segments and sub-segments based on:

  • List of major players operating in the cold plasma   products market at the regional and/or country level
  • Product mapping of various cold plasma   manufacturers at the regional and/or country level
  • Mapping of annual revenue generated by listed major players from cold plasma (or the nearest reported business unit/product category)
  • Revenue mapping of major players to cover at least 70-75% of the global market share as of 2023
  • Extrapolation of the revenue mapping of the listed major players to derive the global market value of the respective segments/subsegments
  • Summation of the market value of all segments/subsegments to arrive at the global point-of-care  diagnostics market

The above-mentioned data was consolidated and added with detailed inputs and analysis from MarketsandMarkets and presented in this report.

Data Triangulation

After arriving at the overall size of the global cold plasma market through the above-mentioned methodology, this market was split into several segments and subsegments. The data triangulation and market breakdown procedures were employed, wherever applicable, to complete the overall market engineering process and arrive at the exact market value data for the key segments and subsegments. The extrapolated market data was triangulated by studying various macro indicators and regional trends from both demand- and supply-side participants.

Market Definition

Plasma is the fourth state of matter. Cold plasma is a partially ionized gas comprising ions, electrons, ultraviolet photons, and reactive neutrals such as radicals and excited & ground-state molecules. It is an innovative and convenient alternative to traditional and conventional technologies used across a wide range of industries, including textiles, electronics & semiconductors, polymers & plastics, medical, cosmetic and food & agriculture.

Stakeholders

  • Cold plasma manufacturers and distributors
  • Government and research organizations
  • Cold plasma application industries
  • Medical device manufacturing companies
  • Healthcare organizations
  • Government associations
  • Market research and consulting firms
  • Venture capitalists and investors
  • Corporate entities

Report Objectives

  • To define, measure, and describe the global cold plasma  market by industry, application, regime, and region
  • To provide detailed information about the major factors influencing the market growth (drivers, restraints, challenges, and opportunities)
  • To strategically analyze the regulatory scenario, pricing, value chain analysis, supply chain analysis, ecosystem analysis, technology analysis, Porter’s Five Forces analysis, and patent analysis
  • To analyze micro markets with respect to individual growth trends, prospects, and contributions to the overall market
  • To analyze market opportunities for stakeholders and provide details of the competitive landscape for key players
  • To forecast the size of market segments in North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa
  • To strategically analyze the market structure, profile the key players in the global cold plasma  market, and comprehensively analyze their core competencies
  • To track and analyze company developments such as acquisitions, partnerships, expansions, and product launches and approvals in the cold plasma  market

Previous Versions of this Report

Cold Plasma Market by Industry (Textile, Electronics & Semiconductors, Polymers & Plastic, Food & Agriculture, Medical, Others), Application (Adhesion, Printing, Wound Healing), Regime (Atmospheric, Low Pressure), COVID-19 Impact - Global Forecast to 2026

Report Code MD 5001
Published in Dec, 2021, By MarketsandMarkets™

Cold Plasma Market by Industry (Textile, Electronics & Semiconductors, Polymer & Plastic, Food & Agriculture, Medical, Others), Application (Adhesion, Etching, Wound Healing), Regime (Atmospheric, Low pressure), COVID-19 Impact - Global Forecast to 2025

Report Code MD 5001
Published in Jul, 2020, By MarketsandMarkets™

Cold Plasma Market by Industry (Textile, Electronics & Semiconductors, Polymer & Plastic, Food & Agriculture, Medical), Application (Adhesion, Etching, Wound Healing, Cancer treatment), Regime (Atmospheric, Low-Pressure), Region - Global Forecast to 2024

Report Code MD 5001
Published in Oct, 2019, By MarketsandMarkets™

Cold Plasma Market by Industry (Textile, Electronics & Semiconductors, Polymer & Plastic, Food & Agriculture, Medical), Application (Adhesion, Etching, Wound Healing, Cancer treatment), Regime (Atmospheric, Low-Pressure), Region - Global Forecast to 2024

Report Code MD 5001
Published in Feb, 2017, By MarketsandMarkets™
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