Clinical Decision Support Systems (CDSS) Companies

The global clinical decision support systems (CDSS) market is projected to reach USD 3.89 billion by 2030 from USD 2.25 billion in 2024, at a CAGR of 9.6% during the forecast period. The market growth is driven by the rising demand for improved patient outcomes and the global emphasis on value-based care. Healthcare systems are increasingly adopting CDSS tools to reduce medical errors, improve diagnostic accuracy, and enhance treatment efficacy. The widespread implementation of electronic health records (EHRs) further supports this trend by enabling seamless integration of decision support tools into clinical workflows.

Strategic partnerships & collaborations and AI-driven innovation are two dominant strategies in the global Clinical Decision Support Systems (CDSS) market. Companies are increasingly forming partnerships to integrate CDSS tools into broader healthcare IT ecosystems, exemplified by the 2023 collaboration between Epic Systems and Microsoft, which focused on embedding AI capabilities within Epic's EHR system. Companies such as Wolters Kluwer Health are advancing AI-driven decision support, with their UpToDate platform using machine learning to enhance evidence-based decision-making and improve clinical outcomes. These strategies are essential in driving CDSS adoption and improving clinical workflows.

To know about the assumptions considered for the study download the pdf brochure

Some of the prominent players operating in the clinical decision support systems market are Wolters Kluwer N.V. (Netherlands), Oracle (US), Merative (US), Change Healthcare (US), Veradigm Inc. (US), athenahealth (US), Epic Systems Corporation (US), Elsevier B.V. (Netherlands), Zynx Health (US), Koninklijke Philips N.V. (Netherlands), Medical Information Technology, Inc. (US), NextGen Healthcare, Inc. (US), CureMD Healthcare (US), Siemens Healthineers (Germany), EBSCO Information Services (US), GE HealthCare (US), eClinicalWorks (US), The Medical Algorithms Company (UK), RAMPmedical (Germany), Hera-MI (France), CareCloud, Inc. (US), VisualDx (US), Premier, Inc. (US), First Databank, Inc. (US), and Strata Decision Technology (US). These companies implemented strategies such as launching products, updating products, expanding their businesses, forming partnerships, collaborating with other key players, and engaging in mergers & acquisitions to enhance their market presence in the clinical decision support systems.

Wolters Kluwer N.V.  (Netherlands) provides comprehensive healthcare solutions, specializing in clinical decision support systems (CDSS). The company offers drug information software, point-of-care tools, bibliographic databases, and online education products that aid healthcare delivery. Its core strength lies in evidence-based, physician-authored clinical decision support resources, which enhance clinical effectiveness, patient safety, and decision-making. UpToDate, its flagship CDSS, is trusted by healthcare professionals for evidence-based insights that improve patient outcomes. Its healthcare portfolio covers clinical drug information, patient engagement, medical research, and nursing solutions, with a focus on continuous learning and safety. Wolters Kluwer operates in over 180 countries and employs approximately 21,400 professionals, delivering advanced solutions that improve healthcare practices and research worldwide.

Oracle (US) provides healthcare information technology (HCIT) solutions, offering services that support clinical, financial, and operational functions across healthcare organizations. In June 2022, Oracle acquired Cerner, forming Oracle Cerner, a wholly owned subsidiary focused on improving patient care and population health management. Oracle Cerner delivers a connected clinical and financial ecosystem supported by offerings across cloud, licensing, hardware, and services. It operates globally across North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa, with strong supplier relationships ensuring a resilient supply chain. The company has advanced its cloud-based clinical decision support systems (CDSS) by integrating them into Electronic Health Records (EHRs) to enhance early cancer detection. These tools use machine learning to analyze patient data, helping clinicians identify cancer risks more accurately and efficiently, thereby improving oncology decision-making at the point of care.

Merative (US), formerly IBM Watson Health, is a key provider in the clinical decision support systems (CDSS) market. After becoming an independent entity under Francisco Partners in 2022, Merative has continued to deliver healthcare solutions across domains such as clinical decision support, healthcare analytics, enterprise imaging, and real-world evidence. Its CDSS tools equip physicians, nurses, and pharmacists with real-time, evidence-based insights at the point of care. According to the blog published by Merative in April 2024, the company emphasized the strategic value of CDSS investments for hospital leadership, urging a focus on evidence-based interventions to prevent medication errors, medication validation at scale to reduce cost and wastage, and streamlined access to information to support clinical efficiency and reduce burnout.

MARKET RANKING

The ranking of companies in the clinical decision support systems (CDSS) market has been determined through a market share analysis, conducted after thorough secondary research and validated by primary respondents. This ranking considers parameters such as revenue generated from clinical decision support systems (CDSS), product portfolio breadth and depth, innovation, and launches. Based on this analysis, the top players leading the market are Oracle (US), Merative (US), Epic Systems Corporation (US), Wolters Kluwer N.V.  (Netherlands), and Verdigm LLC (US).

These companies rely on their strong R&D capabilities, diversified product portfolio, global reach, and continuous innovation in the clinical decision support systems (CDSS) market. With a robust life sciences portfolio including Clinical Research, Real-World Evidence, Safety and Pharmacovigilance, and Oncology Consulting, Oracle has expanded its capabilities through strategic collaborations. In March 2025, Oracle entered an exclusive partnership with NVIDIA Corp (US) to integrate accelerated computing and AI software into Oracle Cloud Infrastructure (OCI), aiming to improve the deployment of AI applications in healthcare. Merative supports clients in R&D and commercialization through data analytics and technologies such as AI, cloud, and blockchain. It emphasized the strategic value of CDSS in 2024 by highlighting the need for evidence-based interventions, medication validation at scale, and streamlined access to clinical insights. Epic Systems continues to enhance its EHR platform to align with CDSS tools, focusing on clinician efficiency and patient outcomes. Wolters Kluwer offers trusted, evidence-based tools such as UpToDate, designed to integrate CDSS directly into clinical workflows, and its 2025–2027 strategy centers on scaling expert solutions and enhancing care delivery. Veradigm LLC advances clinical data exchange by integrating HL7 FHIR-based tools for improved care coordination. In 2025, the company expanded its CDSS capabilities by embedding social determinants of health and mortality data into its EHR database, offering deeper insights into patient care.

Related Reports:

Clinical Decision Support Systems (CDSS) Market by Component (Services, Software), Delivery (On-premise, Cloud), Product (Standalone, Integrated), Application (Advanced, Therapeutic, Diagnostic), Interactivity (Active, Passive) - Global Forecasts to 2030

Contact:
Mr. Rohan Salgarkar
MarketsandMarkets™ INC.
1615 South Congress Ave.
Suite 103, Delray Beach, FL 33445
USA : 1-888-600-6441
sales@marketsandmarkets.com