Protein Expression Market

The report "Protein Expression Market by Product (Reagents, Vectors, Competent Cells, Instruments, Software), Services, System Type (Mammalian (CHO, HEK293), Insect, Yeast), Workflow, Application (Therapeutic, Research, Industrial) - Global Forecast to 2029", is expected to reach USD 4.82 billion by 2029 from an estimated USD 3.41 billion in 2024. Factors such as the increasing demand for biologics including mAbs, ADCs, and other protein-based therapeutics, supported by the rise in R&D in pharmaceutical and biopharmaceutical industries and a growing use of artificial intelligence and machine learning to enhance the protein structure prediction and characterization studies, propel the growth of the protein expression market. Other factors such as the increasing shift toward personalized medicines and growing outsourcing of clinical activities further support the adoption of protein expression products and services. Moreover, the growing emphasis on plant-based and cell-free expression systems and the rising use of recombinant proteins in various industries including food and beverages, textile, and pharmaceutical industries provide growth opportunities to players offering protein expression offerings. However, factors such as the high cost of protein expression reagents and instruments and the dominance of small molecules (non—protein-based therapeutics) in drug development are expected to restrain the growth of this market.

Browse 632 market data Tables and 71 Figures spread through 470 Pages and in-depth TOC on "Protein Expression Market by Product (Reagents, Vectors, Competent Cells, Instruments, Software), Services, System Type (Mammalian (CHO, HEK293), Insect, Yeast), Workflow, Application (Therapeutic, Research, Industrial) - Global Forecast to 2029"
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The Mammalian expression system segment accounted for the largest share of the Protein Expression Market, by system type, during the forecast period.

Based on system type, the protein expression market is divided into mammalian cell expression systems, prokaryotic expression systems, yeast expression systems, cell-free expression systems, insect cell expression systems, and algal-based expression systems. The sizable share of this segment can be attributed to the preference given to these systems for the production of complex proteins required for the development of therapeutic proteins such as mAbs, ADCs, and vaccines. Chinese hamster ovary (CHO) cell expression systems are the most commonly used mammalian expression systems. The ability of these cell lines to undergo rapid growth and achieve high protein expression levels makes them the most adopted mammalian expression system.

The Research applications subsegment emerged as the fastest-growing application segment in the protein expression market in 2023

Based on application, the protein expression market is segmented into therapeutic, research, and industrial applications. The research applications segment accounted for the fastest-growing application segment of the global protein expression market. Factors such as an increase in proteomics, genomics, and drug discovery-based research supported by an increase in institutional and government funding and grants, to support the high growth of the research application segment. This growth trend is expected to continue throughout the forecast period as major pharmaceutical and biotechnology companies invest substantially in research and development of novel protein-based therapies for various diseases.

North America is the largest region and the fastest-growing region of the Protein Expression market in 2023.

The protein expression market is divided into six regions, North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. In 2023, North America held the largest share of the protein expression market, followed by Europe. The presence of major suppliers (Life Science companies) and key end users (Pharmaceutical and biotechnology companies) for the protein expression offerings in the region support the large share of the North American protein expression market. Other factors such as the growth in the biotechnology and pharmaceutical industries, the rising prevalence of chronic disorders, and an increase in investments in the research and development of protein-based therapeutics research further support this large share of this market. This dominance of North America is expected to continue during the forecast period.

Key players in the Protein Expression market include Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany), GenScript Biotech Corporation (US), Agilent Technologies Inc. (US), Danaher Corporation (US), Sartorius AG (Germany), Takara Bio Inc. (Japan), Bio-Rad Laboratories Inc. (US), Lonza Group AG (Switzerland), Charles River Laboratories (US) ,and Eurofins Scientific (Luxembourg).

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