The report "Oral Proteins & Peptides Market by Molecule (Semaglutide, Linaclotide, Calcitonin), Drug Class (GLP-1 Receptor Agonist, GEP, CGRP), Therapeutic Area (Diabetes, Gastroenterology, Genetic Disorder), Formulation (Tablet, Capsule) - Global Forecast to 2030", is expected to reach USD 24.00 billion by 2030 from USD 8.85 billion in 2025, at a CAGR of 22.1% during the forecast period from 2025 to 2030. Several factors are contributing to this growth, including the rising prevalence of chronic diseases such as diabetes, gastrointestinal disorders, and kidney diseases. Additionally, patients' preference for and compliance with the oral route of drug administration and increasing adoption of inorganic growth strategies, such as collaborations and partnerships for research and development, are also driving market expansion. However, challenges such as formulation and stability issues and a stringent regulatory approval process are expected to hinder market development.
Browse 407 market data Tables and 53 Figures spread through 323 Pages and in-depth TOC on "Oral Proteins & Peptides Market by Molecule (Semaglutide, Linaclotide, Calcitonin), Drug Class (GLP-1 Receptor Agonist, GEP, CGRP), Therapeutic Area (Diabetes, Gastroenterology, Genetic Disorder), Formulation (Tablet, Capsule) - Global Forecast to 2030"
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The semaglutide segment accounted for the largest share of the molecule segment in the oral proteins and peptides market in 2024.
The oral proteins and peptides market is segmented by molecule into several categories, including trofinetide, semaglutide, linaclotide, voclosporin, plecanatide, calcitonin, and others. In 2024, the semaglutide segment dominated the market and is expected to continue leading throughout the forecast period. The strong growth of this segment can be attributed to several factors, such as the increasing prevalence of diabetes and the rising demand for oral proteins and peptides due to their benefits, including ease of use and high patient compliance. Semaglutide is an analog of glucagon-like peptide-1 (GLP-1), a hormone crucial in regulating blood sugar levels and appetite. It is primarily used for managing type 2 diabetes.
The tablets segment is estimated to register the highest growth rate during the forecast period in the oral proteins and peptides market, by formulation, in 2024.
The oral proteins and peptides market is segmented based on formulation into tablets, capsules, and oral solutions. Among these, the tablets segment is expected to experience the highest growth rate during the forecast period. Several key factors contribute to this growth, including the advantages offered by tablets, such as precise drug dosing, greater stability compared to capsules, a longer shelf life, ease of use, and affordability. Additionally, these formulations allow for controlled release, which enhances bioavailability and ensures consistent therapeutic effects. Tablets are also cost-effective to manufacture and distribute, promoting wider accessibility and scalability in commercial production.
Europe is the second-largest region in the oral proteins and peptides market.
The oral proteins and peptides market is divided into six major regions: North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. Europe is the second-largest market for oral proteins and peptides globally. Several key factors contribute to the growth of this market. These include the strong presence of major players offering oral proteins and peptides, a favorable regulatory environment, and the wide availability of these products in the region, with reimbursement options provided in several countries.
Key players in the oral proteins and peptides market include Novo Nordisk A/S (Denmark), AbbVie Inc. (US), Pfizer Inc. (US), Acadia Pharmaceuticals Inc. (US), Aurinia Pharmaceuticals Inc. (Canada), Bausch Health Companies Inc. (Canada), CHIESI Farmaceutici S.p.A. (Italy), EnteraBio Ltd. (Israel), Merck & Co., Inc. (US), Johnson & Johnson Services, Inc. (US), R-Pharm JSC (Russia), Proxima Concepts (US), SWK Holdings Corporation (US), AstraZeneca (UK), Regor Therapeutics Group (China), Viking Therapeutics (US), Protagonist Therapeutics Inc. (US), Rani Therapeutics Holdings, Inc. (US), Carmot Therapeutics, Inc. (US), Terns Pharmaceuticals, Inc. (US), Structure Therapeutics (US), Zealand Pharma (Denmark), Sciwind Biosciences (China), and Jiangsu Hengrui Pharmaceuticals Co., Ltd. (China).
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