Pulmonary Arterial Hypertension Market by Drug Class (SGC Stimulators, Endothelin Receptor Antagonists, Type (Innovative, Generics) – Global Forecast to 2027
The global pulmonary arterial hypertension market is projected to reach USD 9 billion by 2027 from USD 7 billion in 2022, at a CAGR of 5% during the forecast period
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Pulmonary hypertension is high blood pressure in the pulmonary arteries, which carry oxygen-poor blood from heart to lungs. The major symptoms are shortness of breath, chest pain or pressure, dizziness or fainting, fatigue, and others. According to The American Journal of Managed Care, PAH is a rare disorder found in 15 to 50 persons per million within the United States and Europe. Idiopathic, heritable, and anorexigen-induced PAH make up 52.6% of all PAH cases. Usually, PAH affects women aged between 30 and 60 years. The rising prevalence of the PAH across the globe is increasing the demand for treatment options, these factors are likely to have higher impact on the market growth in coming years.
In the report, the pulmonary arterial hypertension market is segmented into drug class, type, route of administration, distribution channel and region. Based on the drug class the market is segmented into endothelin receptor antagonists, SGC Stimulators, PDE-5 Inhibitors, prostacyclin and prostacyclin analogs and others. Increase in number of FDA approvals in the prostacyclin and prostacyclin analogs drug class is likely to have higher impact on the adoption and sales across the globe. For instance, In July 2021, Uptravi belonging to Prostacyclin and Prostacyclin Analogs segment received FDA approval for intravenous use in pulmonary arterial hypertension patients. Various SGC stimulators products under phase 2 and phase 3 clinical trials are likely to get approvals during the forecast period. For instance, Merck Sharp & Dohme LLC, candidate MK-5475 is under phase 2 clinical trial and expected to be launch in coming 3-4 years. The study is for MK-5475, an inhaled soluble guanylate cyclase stimulator, in participants with pulmonary arterial hypertension (PAH).
Based on region the market is further divided into North America, Europe, Asia Pacific, and ROW (Rest of the World). Among the region North America is expected hold dominant share throughout the forecast period. The dominance is attributed to rising incidence & prevalence of pulmonary arterial hypertension in the region. Furthermore, rising investment in development & launch of new drugs in the market is likely to increase consumption hence contributing towards revenue growth in the region.
The major players operating in the pulmonary arterial hypertension market are United Therapeutics Corporation (US), BAYER (Germany), Gilead Sciences, Inc. (US), Johnson & Johnson (US), Viatris Inc. (US), Teva Pharmaceutical Industries Ltd. (Israel) and among others.
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Scope of the Report
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Pulmonary arterial hypertension (PAH) is a rare, progressive disorder characterized by high blood pressure (hypertension) in the arteries of the lungs (pulmonary artery) for no apparent reason. PAH occurs 3-5 times more often in females than in males. It tends to affect females between the ages of 30 and 60. Around 500-1000 new cases of PAH are diagnosed each year in the U.S. Rising prevalence is increasing demand for the treatment options hence projecting the market growth.
Global Pulmonary Arterial Hypertension Market
The research report categorizes the Pulmonary Arterial Hypertension Market into following segments.
Pulmonary Arterial Hypertension Market, By Drug Class
- Endothelin Receptor Antagonists
- SGC Stimulators
- PDE-5 Inhibitors
- Prostacyclin &Prostacyclin Analogs
- Others
Pulmonary Arterial Hypertension Market, By Route of Administration
- Oral
- Intravenous/ Subcutaneous
- Others
Pulmonary Arterial Hypertension Market, By Type
- Innovative
- Generics
Pulmonary Arterial Hypertension Market, By Distribution Channel
- Hospitals
- Retail Pharmacies
- Online Pharmacies
Pulmonary Arterial Hypertension Market, By Region
- North America
- US
- Canada
- Europe
- Germany
- France
- UK
- ROE
- Asia Pacific
- Japan
- China
- India
- Rest Of APAC
- Rest Of the World (Row)
- Latin America
- Middle East & Africa
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TABLE OF CONTENTS
1 INTRODUCTION
1.1 OBJECTIVES OF THE STUDY
1.2 MARKET DEFINITION
1.2.1 INCLUSIONS & EXCLUSIONS
1.3 MARKET SCOPE
1.3.1 MARKET COVERED
1.3.2 YEARS CONSIDERED FOR THE STUDY
1.4 CURRENCY
1.5 LIMITATIONS
1.6 STAKEHOLDERS
2 RESEARCH METHODOLOGY
2.1 RESEARCH DATA
2.1.1 SECONDARY DATA
2.1.2 PRIMARY DATA
2.1.2.1 Key industry insights
2.2 MARKET SIZE ESTIMATION
2.3 MARKET GROWTH RATE PROJECTIONS
2.4 MARKET BREAKDOWN AND DATA TRIANGULATION
2.5 ASSUMPTIONS FOR THE STUDY
3 EXECUTIVE SUMMARY
4 PREMIUM INSIGHTS
5 MARKET OVERVIEW
5.1 INTRODUCTION
5.2 MARKET DYNAMICS
5.2.1 DRIVERS
5.2.2 RESTRAINTS
5.2.3 OPPORTUNITIES
5.2.4 CHALLENGES
5.3 TRENDS/DISRUPTIONS IMPACTING CUSTOMER’S BUSINESS
5.4 PRICING ANALYSIS
5.5 VALUE CHAIN ANALYSIS
5.6 ECOSYSTEM ANALYSIS
5.7 PATENT ANALYSIS
5.8 KEY CONFERENCES AND EVENTS IN 2022-2023
5.9 REGULATORY ANALYSIS
5.10 PORTER’S FIVE FORCES ANALYSIS
5.11 KEY STAKEHOLDER AND BUYING CRITERIA
6 PULMONARY ARTERIAL HYPERTENSION MARKET, BY DRUG CLASS, 2020-2027 (USD MILLION)
6.1 INTRODUCTION
6.2 ENDOTHELIN RECEPTOR ANTAGONISTS
6.3 SGC STIMULATORS
6.4 PDE-5 INHIBITORS
6.5 PROSTACYCLIN AND PROSTACYCLIN ANALOGS
6.6 OTHERS
7 PULMONARY ARTERIAL HYPERTENSION MARKET, BY ROUTE OF ADMINISTRATION, 2020-2027 (USD MILLION)
7.1 INTRODUCTION
7.2 ORAL
7.3 INTRAVENOUS/ SUBCUTANEOUS
7.4 OTHERS
8 PULMONARY ARTERIAL HYPERTENSION MARKET, BY TYPE, 2020-2027 (USD MILLION)
8.1 INTRODUCTION
8.2 INNOVATIVE
8.3 GENERICS
9 PULMONARY ARTERIAL HYPERTENSION MARKET, BY DISTRIBUTION CHANNEL, 2020-2027 (USD MILLION)
9.1 INTRODUCTION
9.2 HOSPITALS
9.3 RETAIL PHARMACIES
9.4 ONLINE PHARMACIES
10 PULMONARY ARTERIAL HYPERTENSION MARKET, BY REGION, 2020-2027 (USD MILLION)
10.1 INTRODUCTION
10.2 NORTH AMERICA
10.2.1 US
10.2.2 CANADA
10.3 EUROPE
10.3.1 GERMANY
10.3.2 FRANCE
10.3.3 UK
10.3.4 ROE
10.4 ASIA PACIFIC
10.4.1 JAPAN
10.4.2 CHINA
10.4.3 INDIA
10.4.4 REST OF APAC
10.5 REST OF THE WORLD (ROW)
10.5.1 LATIN AMERICA
10.5.2 MIDDLE EAST & AFRICA
11 COMPETITIVE LANDSCAPE
11.1 OVERVIEW
11.2 KEY PLAYER STRATEGIES
11.3 REVENUE SHARE ANALYSIS OF TOP MARKET PLAYERS
11.4 MARKET SHARE ANALYSIS, 2021
11.5 COMPANY EVALUATION QUADRANT
11.6 COMPANY EVALUATION QUADRANT – SME/START-UPS
11.7 COMPANY GEOGRAPHIC FOOTPRINT
11.8 COMPETITIVE SCENARIO
12 COMPANY PROFILES
(The details on business overview, financial information, products/services portfolio, recent developments, MarketsandMarkets view will be provided)*
12.1 UNITED THERAPEUTICS CORPORATION
12.2 BAYER
12.3 GILEAD SCIENCES, INC.
12.4 JOHNSON & JOHNSON
12.5 VIATRIS INC
12.6 TEVA PHARMACEUTICAL INDUSTRIES LTD.
12.7 ACTELION PHARMACEUTICALS LTD.
12.8 LUPIN
12.9 SUN PHARMACEUTICAL INDUSTRIES LTD.
12.10 GSK PLC
12.11 ELI LILLY AND COMPANY
12.12 PFIZER INC
* Details on business overview, financial information, products/services portfolio, recent developments, MarketsandMarkets view might not be captured in case of unlisted companies.
12 APPENDIX
12.1 INSIGHTS FROM INDUSTRY EXPERTS
12.2 DISCUSSION GUIDE
12.3 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL
12.4 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE
12.5 AVAILABLE CUSTOMIZATIONS
12.6 RELATED REPORTS
12.7 AUTHOR DETAILS
Growth opportunities and latent adjacency in Pulmonary Arterial Hypertension Market