Cell Expansion Market by Product (Consumables (Media, Sera, Reagents, Vessels), Equipment (Cell Expansion Systems, Bioreactors, Incubators)), Cell Type (Human, Animal (CHO, mESCs)), Application (Vaccines, mAbs, CGT), End User - Global Forecast to 2029
The global cell expansion market in terms of revenue was estimated to be worth $14.3 billion in 2024 and is poised to reach $26.7 billion by 2029, growing at a CAGR of 13.3% from 2024 to 2029. The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. Growth of the cell expansion market can be attributed to factors such as the booming biopharmaceutical industry, increased investments in research and development for the advancement of biopharmaceutical industry, rising need of advanced biopharmaceuticals, and increasing GMP certification for cell therapy manufacturing facilities. However, ethical concern for cell based research and high cost of cell & gene therapy may hamper the growth of the market.
Cell Expansion Market - Global Forecast to 2029
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Attractive Opportunities in the Cell Expansion Market
Global Cell Expansion Market Dynamics
DRIVER: Increasing rate of chronic diseases
The increasing rate of chronic diseases is propelling the demand for advanced drug therapy products, resulting to boost the growth of cell expansion market. With an aging population, the prevalence of chronic diseases like cancer and diabetes is increasing, this has led to a higher demand for cell-based therapies, driving the need for cell expansion technologies. For instance, according to the American Cancer Society, there were an estimated 1.9 million new cancer cases and 609,360 cancer deaths reported in the US in 2022. Furthermore, Major companies are investing heavily in R&D to improve therapeutics and to meet the growing demand for cellular therapies which is supporting the growth of cell expansion market. Additionally, advancements in automation and bioprocessing technologies are propelling the growth of cell expansion market.
RESTRAINT: Ethical concern related to cell biology
Ethical concerns in cell biology pose a significant restraint on the cell expansion market. One major concern is the use of embryonic stem cells, which raises ethical concern about the destruction of human embryos. This has led to restrictions on the use of embryonic stem cells in many countries, limiting their availability for research and therapeutic applications. Another ethical issue is related to the sourcing of cells for expansion. While adult stem cells offer an ethical alternative to embryonic stem cells, their extraction often involves invasive procedures, raising concerns about patient consent and safety. Additionally, there are ethical considerations surrounding the use of genetically modified cells and potential risks to both patients and the environment. Thus, ethical concern regarding cell biology is hindering the growth of cell expansion market.
OPPORTUNITY: Growth opportunities in emerging economies
Emerging countries such as China, India, Brazil, and Mexico are expected to show significant growth opportunities for players operating in the cell expansion market driven by factors such as rising healthcare expenditure, expanding manufacturing capabilities, growing biopharmaceutical sector, technological advancements, expansion of key market players, and rising government support. By leveraging these opportunities, major market players are expanding their footprints in emerging economies and contribute to improving access to quality healthcare products across the globe.
CHALLENGE: Issues related to supply chain and logistics
Supply chain and logistics pose significant challenges for the cell expansion market. One major issue is the complex and fragile nature of cell-based products, which require stringent temperature control and specialized handling throughout the supply chain. Additionally, the global nature of the cell expansion market presents logistical challenges related to international shipping and regulatory compliance. Government regulations vary across regions, requiring companies to navigate complex import or export procedures and documentation requirements. Delays in customs clearance and regulatory approvals can disrupt supply chains and impact the timely delivery of cell-based therapies to patients.
Global Cell Expansion Industry Ecosystem Analysis
The cell expansion market ecosystem comprises raw material suppliers, cell expansion product manufacturers, and end users such as pharmaceutical and biotechnology companies, research & academic institutes, hospitals & diagnostic laboratories, CROs, CDMOs, and cell banks. Cell expansion products manufacturers provide consumables including media, reagents, sera, vessels, and other consumables, and equipment such as bioreactors, automated cell expansion systems, and other cell expansion equipment.
The human cells segment dominated cell expansion industry in 2023
Based on cell type, the cell expansion market is segmented into three major segments, namely, human cells, animal cells, and other cell types. In 2023, human cells segment dominated the market owing to rising research activities for the development of cell based therapeutics such as regenerative medicine and cell & gene therapies. Moreover, rising R&D spendings by the government and major market players are propelling the adoption of human cells for manufacturing of cell based therapeutics, resulting to drive the segment growth in cell expansion market.
The pharmecutical & biotechnology companies segment dominated the cell expansion industry in 2023
Based on end user, the cell expansion market is segmented into pharmaceutical & biotechnology companies, research & academic institutes, hospitals & clinics, and other end users. In 2023, pharmaceutical & biotechnology companies segment held the largest market share in the global market owing to rising demand for manufacturing of novel therapeutics. Futher, growing focus on personalized medicine is promoting the segment growth is cell expansion market.
North America dominated the cell expansion industry in 2023.
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The global cell expansion market is segmented into six major regions—North America, Europe, the Asia Pacific, Latin America, Middle East, and Africa. North America accounted for the largest of cell expansion market in 2023, followed by Europe and the Asia Pacific. Factors such as significant expenditure on R&D activities, presence of a well-established healthcare market, growing demand for cell based therapeutics, among others are responsible for the largest share of this segment.
Key players in the cell expansion market include Thermo Fisher Scientific, Inc. (US), Danaher Corporation (US), Merck KGaA (Germany), Sartorius AG (Germany), Corning Incorporated (US), Lonza (Switzerland), Terumo Corporation (Japan), Eppendorf SE (Germany), FUJIFILM Corporation (Japan), Bio-Techne (US), Repligen Corporation (US), Getinge AB (Sweden), Miltenyi Biotec (Germany), PerkinElmer Inc. (US), STEMCELL Technologies (Canada), PromoCell GmBH (Germany), HiMedia Laboratories (India), BD (US), Takara Bio Inc. (Japan), Shanghai Duoning Biotechnology Co., Ltd. (Japan), REPROCELL Inc. (Japan), PBS Biotech, Inc. (US), ACROBiosystems (US), Solida Biotech GmBH (Germany), Beijing CytoNiche Biotechnology Co., Ltd. (China), Neuromics (US), Bionet (Spain), and Cellexus (UK).
Scope of the Cell Expansion Industry
|
Report Metric |
Details |
|
Market Revenue in 2024 |
$14.3 billion |
|
Projected Revenue by 2029 |
$26.7 billion |
|
Revenue Rate |
Poised to Grow at a CAGR of 13.3% |
|
Market Driver |
Increasing rate of chronic diseases |
|
Market Opportunity |
Growth opportunities in emerging economies |
This report categorizes the global cell expansion market to forecast revenue and analyze trends in each of the following submarkets:
By Product
-
Consumables
-
Media
- Serum-free Media
- Classical Media & Salts
- Stem Cell Culture Media
- Chemically Defined Media
- Specialty Media
- Other Media
- Reagents
- Sera
-
Vessels
- Roller/roux bottles
- Cell factory systems/cell stacks
- Flasks
- Multiwell plates
- Cell Expasnion Bags
- Petri dishes
- Other Consumables
-
Media
-
Equipment
-
Bioreactors
-
Bioreactors, by Usage
- Conventional Bioreactors
- Single Use Bioreactor
-
Bioreactors, by Type
- Microcarrier bioreactor
- Suspension based independent bioreactors
- Hollow fiber bioreactor
- Other Bioreactors
-
Bioreactors, by Usage
- Automated cell expansion systems
- Other Cell Expansion Equipment
-
Bioreactors
By Cell Type
-
Human Cells
-
Stem Cells
- Adult Stem Cells
- Embryonic Stem Cells
- Induced Pluripotent Stem Cells
- Differenciated Cells
-
Stem Cells
-
Animal Cells
- Chinese Hamster Ovary Cells (CHO)
- Mouse Embryonic Stem Cells (mESCs)
- Others Animal Cells
- Other Cell Types
By Application
-
Biopharmaceutical Production
- Monoclonal Antibody Production
- Vaccine Production
- Other Therapeutic Protein Production
-
Tissue Engineering & Regenerative Medicine
- Cell And Gene Therapy
- Other Tissue Engineering And Regenerative Medicine Applications
- Drug Screening & Development
- Other Applications
By End User
- Pharmaceutical & Biotechnology Companies
- Research & Academic Institutes
- Hospitals And Diagnostic Laboratories
- Other End Users
By Region
-
North America
- US
- Canada
-
Europe
- Germany
- UK
- France
- Italy
- Spain
- Rest of Europe (RoE)
-
Asia Pacific (APAC)
- China
- Japan
- India
- South Korea
- Australia
- Rest of Asia Pacific (RoAPAC)
-
Latin America
- Brazil
- Mexico
- Rest of Latin America (RoLATAM)
-
Middle East
-
GCC Countries
- Saudi Arabia (KSA)
- United Arab Emirates (UAE)
- Rest of GCC Countries (RoGCC)
- Rest of Middle East (RoME)
-
GCC Countries
- Africa
Recent Developments of Cell Expansion Industry:
- In April 2023, Danaher Corporation (Cytiva) launched X-platform bioreactors to simplify single-use upstream bioprocessing operations. The X-platform bioreactors can be used to manufacture monoclonal antibodies, cell & gene therapies, and viral vectors. The bioreactors are customizable and scalable and are expected to increase productivity in process development and manufacturing.
- In December 2022, Merck acquired Erbi Biosystems, a developer of the 2 ml micro-bioreactor platform technology, known as the Breez. The acquisition aims to strengthens Merck’s upstream portfolio in therapeutic proteins by enabling scalable cell-based perfusion bioreactor processes from 2ml to 2000L with rapid lab-scale process development.
Frequently Asked Questions (FAQ):
What is the projected market revenue value of the global cell expansion market?
The global cell expansion market boasts a total revenue value of $26.7 billion by 2029.
What is the estimated growth rate (CAGR) of the global cell expansion market?
The global cell expansion market has an estimated compound annual growth rate (CAGR) of 13.3% and a revenue size in the region of $14.3 billion in 2024. .
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This research study involved the extensive use of secondary sources, directories, and databases to identify and collect valuable information for the analysis of the global cell expansion market. In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, to obtain and verify critical qualitative and quantitative information and assess the growth prospects of the market. The global market size estimated through secondary research was then triangulated with inputs from primary research to arrive at the final market size.
Secondary Research
Secondary research was used mainly to identify and collect information for the extensive, technical, market-oriented, and commercial study of the cell expansion market. The secondary sources used for this study include World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), US Food and Drug Administration (FDA), South African Medical Research Council, International Society for Cell & Gene Therapy (ISCT), International Business Magazine, Nasdaq, Center for Strategic & International Studies (CSIS), American Society of Gene & Cell Therapy, Statista; corporate filings such as annual reports, SEC filings, investor presentations, and financial statements; press releases; trade, business, professional associations and among others. These sources were also used to obtain key information about major players, market classification, and segmentation according to industry trends, regional/country-level markets, market developments, and technology perspectives.
Primary Research
Extensive primary research was conducted after acquiring basic knowledge about the global cell expansion market scenario through secondary research. Several primary interviews were conducted with market experts from the demand side, such as pharmaceutical and biopharmaceutical companies, research & academic institutes, hospitals & diagnostic laboratories, CROs, and CMOs, and experts from the supply side, such as C-level and D-level executives, product managers, marketing & sales managers of key manufacturers, distributors, and channel partners. These interviews were conducted across six major regions, including the Asia Pacific, North America, Europe, Latin America, Middle East, and Africa. Approximately 60% and 40% of the primary interviews were conducted with supply-side and demand-side participants, respectively. This primary data was collected through questionnaires, e-mails, online surveys, personal interviews, and telephonic interviews.
The following is a breakdown of the primary respondents:
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Market Size Estimation
Both top-down and bottom-up approaches were used to estimate and validate the total size of the cell expansion market. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:
Bottom-up Approach
- The key players in the industry and market have been identified through extensive secondary research
- The revenues generated from the cell expansion business of leading players have been determined through primary and secondary research
- All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources
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Top-down Approach
After arriving at the overall market size from the market size estimation process, the total market was split into several segments and subsegments.
Data Triangulation
After arriving at the market size from the market size estimation process explained above, the total market was divided into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides.
Market Definition
Cell expansion is a process of increasing the number of cells through cell division. Cell expansion is often used for research and therapeutic applications. Cell expansion is also used for manufacturing of cell based therapies such as tissue engineering, cell & gene therapy, and regenerative medicine.
Stakeholders
- Cell Expansion Product Manufacturers, Vendors, and Distributors
- Academic and Research Institutes
- Pharmaceutical and Biotechnology Companies
- Hospitals and Diagnostic Laboratories
- Venture Capitalists and Investors
- Private Research Firms
- Contract Research Organizations (CROs)
- Contract Development and Manufacturing Organizations (CDMOs)
Report Objectives
- To define, describe, and forecast the global cell expansion market based on the product, cell type, application, end user, and region
- To provide detailed information regarding the major factors influencing the growth of the market (such as drivers, restraints, opportunities and challenges)
- To strategically analyze micro-markets with respect to individual growth trends, future prospects, and contributions to the overall cell expansion market
- To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
- To forecast the size of the market segments with respect to six main regions, namely, North America, Europe, Asia Pacific, Latin America, Middle East, and Africa
- To strategically profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
- To track and analyze competitive developments such as acquisitions, product launches, expansions, and R&D activities in the cell expansion market.
Available Customizations
With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for this report:
Portfolio Assessment
- Product Matrix, which gives a detailed comparison of the product portfolios of the top three companies.
Company Information
- Detailed analysis and profiling of additional market players (up to three).
Geographical Analysis
- A further breakdown of the Rest of Asia Pacific cell expansion market into countries
- A further breakdown of the Rest of Europe cell expansion market into countries
- A further breakdown of the Rest of Latin American cell expansion market into countries
- A further breakdown of the Rest of Middle East cell expansion market into countries
Generating Response ...
Growth opportunities and latent adjacency in Cell Expansion Market