Cartilage Repair Market / Cartilage Regeneration Market by Treatment Modalities (Cell-Based (Chondrocyte Transplantation, Stem Cells, Growth Factors), Non-Cell (Tissue Scaffolds)), Application (Hyaline, Fibrocartilage), Site, and Region - Global Forecast to 2028
The global cartilage repair market in terms of revenue was estimated to be worth $1.3 billion in 2023 and is poised to reach $2.8 billion by 2028, growing at a CAGR of 17.2% from 2023 to 2028. The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. Increasing number of osteoarthritis cases, increasing growth opportunities in emerging markets, growing number of Mergers, acquisitions, contracts and agreements between market players and developing healthcare infrastructure.
Attractive Opportunities in the Cartilage Repair Market
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Global Cartilage Repair Market Dynamics
Driver: Increasing number of osteoarthritis cases
Over the years, the incidence of osteoarthritis has increased across the globe. According to WHO data from July 2023, about 528 million people worldwide were living with osteoarthritis in 2019, an increase of 113% since 1990. About 73% of people living with osteoarthritis are older than 55 years, and 60% are female. With a prevalence of 365 million, the knee is the most frequently affected joint, followed by the hip and the hand.
According to the Lancet (August 2023), a new study revealed the most common form of arthritis, osteoarthritis, affects 15% of the global population over the age of 30. In 2020, obesity was responsible for approximately 20% of the disability of osteoarthritis. By 2050, nearly 1 billion people are projected to have osteoarthritis.
Some of the most used treatments for osteoarthritis are autologous chondrocyte implantation and scaffold implants. Thus, the increasing incidence of osteoarthritis is expected to drive the demand for cartilage repair and regeneration products.
Restraint: High cost of cartilage repair surgeries
Cartilage repair surgeries are costly though they have better and longer-lasting treatment results as compared to total knee replacement surgeries. As the high cost of cartilage repair therapies is the major factor that is limiting their adoption of the cartilage repair procedures mainly in the developing countries. Therefore, knee replacement procedures average cost is around USD 16,000 where as cartilage repair procedures average cost is approximately USD 18,000–USD 23,000. These barriers may be more pronounced in low-resource settings and developing countries, which is restricting the growth of the cartilage repair market.
Opportunity: Technological advancements
Challenge: Limitations of cartilage-based stem cell products
Clinical research are ongoing to identify an universal source of progenitor cells like embryonic and induced pluripotent stem cells for the treatment of cartilage repair. However, there are challenges associated with their clinical use like immune rejection, tumorigenesis, and teratoma formation as various authorities such as the Human Tissue Authority (HTA), Human Fertilization and Embryology Authority (HFEA), Medicines and Healthcare Products Regulatory Agency (MHRA), and the Central Ethics Committee for Stem Cell Research to monitor these activities have been formulated. Hence, due to the presence of these regulatory organizations and ethical concerns on the use of embryonic stem cells in research and development is restricted globally.
Cartilage Regeneration Industry Ecosystem
Prominent companies in this market include well-established manufacturers of Cartilage Repair/Cartilage Regeneration Market and offer a wide range of products. These companies have been operating in the market for several years and possess a diversified product portfolio, state-of-the-art technologies, and strong global sales and marketing networks. Prominent companies in this market include Smith+Nephew (UK), DePuy Synthes (Johnson & Johnson) (US), Zimmer Biomet Holdings, Inc. (US), Stryker Corporation (US), and Vericel Corporation (US)
In 2022, Hyaline Cartilage segment to observe highest growth rate of the cartilage regeneration industry, by Application.
Based on the Application, The cartilage repair market, by application, has been segmented into Hyaline Cartilage and Fibrocartilage. Hyaline Cartilage will drive the growth of the market due to growing number of contracts and agreements between key market players and the availability of funding and rising investment in the research and development of the advancement of tissue-engineered products for the treatment of cartilage injury/damage.
In 2022, Knee segment to dominate the cartilage repair industry, by the Application site.
Based on Application site, the cartilage regeneration market is segmented knee, hip, Ankle and foot and other application site. Knee segment is expected to grow highest due to the increasing number of Knee arthroscopy procedures. As Arthroscopic surgery is often used for cartilage reattachment as well as the microfracture technique.
In 2022, North America to dominate the cartilage repair industry, by the Application site as knee segment had the highest growth the region.
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The cartilage repair market is dominated by players such as Smith+Nephew (UK), DePuy Synthes (Johnson & Johnson) (US), Zimmer Biomet Holdings, Inc. (US), Stryker Corporation (US), and Vericel Corporation (US).
Scope of the Cartilage Repair Industry
Report Metric |
Details |
Market Revenue in 2023 |
$1.3 billion |
Projected Revenue by 2028 |
$2.8 billion |
Revenue Rate |
Poised to Grow at a CAGR of 17.2% |
Market Driver |
Increasing number of osteoarthritis cases |
Market Opportunity |
Technological advancements |
This research report categorizes the cartilage regeneration market into the following segments and subsegments:
TYPE |
PARAMETER |
By Region |
|
By Treatment Modality |
|
By Application |
|
By Application Site |
|
Frequently Asked Questions (FAQ):
What is the projected market revenue value of the global cartilage repair market?
The global cartilage repair market boasts a total revenue value of $2.8 billion by 2028.
What is the estimated growth rate (CAGR) of the global cartilage repair market?
The global cartilage repair market has an estimated compound annual growth rate (CAGR) of 17.2% and a revenue size in the region of $1.3 billion in 2023.
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The objective of the study is to analyze the key market dynamics, such as drivers, opportunities, challenges, restraints, and key player strategies. To track company developments such as acquisitions, product launches, expansions, collaborations, agreements, and partnerships of the leading players, the competitive landscape of the cartilage repair/cartilage regeneration market to analyze market players on various parameters within the broad categories of business and product strategy. Top-down and bottom-up approaches were used to estimate the market size. To estimate the market size of segments and subsegments, the market breakdown and data triangulation were used.
The four steps involved in estimating the market size are:
Collecting Secondary Data
The secondary research data collection process involves the usage of secondary sources, directories, databases (such as Bloomberg Businessweek, Factiva, and D&B), annual reports, investor presentations, and SEC filings of companies. Secondary research was used to identify and collect information useful for the extensive, technical, market-oriented, and commercial study of the cartilage repair/cartilage regeneration market. A database of the key industry leaders was also prepared using secondary research.
Collecting Primary Data
The primary research data was collected after acquiring knowledge about the cartilage repair/cartilage regeneration market scenario through secondary research. A significant number of primary interviews were conducted with stakeholders from both the demand side (such as Hospitals) and supply side (such as included various industry experts, such as Directors, Chief X Officers (CXOs), Vice Presidents (VPs) from business development, marketing, and product development teams, product manufacturers, wholesalers, channel partners, and distributors) across major countries of North America, Europe, Asia Pacific and Rest of the world. Approximately 40% of the primary interviews were conducted with stakeholders from the demand side, while those from the supply side accounted for the remaining 60%. Primary data for this report was collected through questionnaires, emails, and telephonic interviews.
A breakdown of the primary respondents is provided below:
Breakdown of Primary Participants:
Note 1: *Others include sales managers, marketing managers, and product managers.
Note 2: Tiers are defined based on a company’s total revenue as of 2022: Tier 1=> USD 1 billion, Tier 2 = USD 500 million to USD 1 billion, and Tier 3=< USD 500 million.
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COMPANY NAME |
DESIGNATION |
Vericel Corporation (US) |
Product Manager |
Zimmer Biomet Holdings, Inc. (US) |
Regional Manager |
Smith+Nephew (UK) |
Regional Business Head |
Market Size Estimation
All major product manufacturers offering various cartilage repair/cartilage regeneration markets were identified at the global/regional level. Revenue mapping was done for the major players and was extrapolated to arrive at the global market value of each type of segment. The market value cartilage repair/cartilage regeneration market was also split into various segments and subsegments at the regional and country levels based on the following:
- Product mapping of various manufacturers for each solution of cartilage repair/cartilage regeneration market at the regional and country-level
- Relative adoption pattern of each cartilage repair/cartilage regeneration market among key application segments at the regional and/or country-level
- Detailed primary research to gather qualitative and quantitative information related to segments and subsegments at the regional and/or country level.
- Detailed secondary research to gauge the prevailing market trends at the regional and/or country level
Global Cartilage Repair/Cartilage Regeneration Market Size: Botton-Up Approach
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Global Cartilage Repair/Cartilage Regeneration Market Size: Top-Down Approach
Data Triangulation
After arriving at the overall market size—using the market size estimation processes—the market was split into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics of each market segment and subsegment, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides in the cartilage repair/cartilage regeneration market.
Market Definition
Cartilage repair refers to the process of restoring damaged or injured cartilage tissue, which is a tough, flexible connective tissue found in various parts of the body, including joints. Cartilage does not have a direct blood supply, which makes its natural healing capacity limited. Therefore, injuries to cartilage often result in pain and limited joint function. The cartilage tissue is made of specialized cells called chondrocytes. Cartilage injuries are most commonly observed in athletes and individuals with an active lifestyle. As cartilage is avascular and does not have a blood supply, cartilage repair and regeneration is one of the most challenging medical treatments. Cartilage repair treatment involves the repair, removal, replacement, or restoration of the surface of articular cartilage.
Key Stakeholders
- Senior Management
- End User
- Finance/Procurement Department
- R&D Department
Report Objectives
- To provide detailed information about the factors influencing the market growth (such as drivers, restraints, opportunities, and challenges)
- To define, describe, segment, and forecast the cartilage repair/cartilage regeneration market by Product, Application, Medical specialty and Region
- To analyze market opportunities for stakeholders and provide details of the competitive landscape for key players
- To analyze micro markets with respect to individual growth trends, prospects, and contributions to the overall cartilage repair/cartilage regeneration market
- To forecast the size of the cartilage repair/cartilage regeneration market in four main regions along with their respective key countries, namely, North America, Europe, the Asia Pacific, and Rest of the world
- To profile key players in the cartilage repair/cartilage regeneration market and comprehensively analyze their core competencies and market shares
- To track and analyze competitive developments, such as acquisitions; product launches; expansions; collaborations, agreements, & partnerships; and R&D activities of the leading players in the cartilage repair/cartilage regeneration market.
- To benchmark players within the cartilage repair/cartilage regeneration market using the Competitive Leadership Mapping framework, which analyzes market players on various parameters within the broad categories of business and product strategy.
Available Customizations
MarketsandMarkets offers the following customizations for this market report:
- Additional country-level analysis of the cartilage repair/cartilage regeneration market
- Profiling of additional market players (up to 5) Product Analysis
- Product matrix, which provides a detailed comparison of the product portfolio of each company in the cartilage repair/cartilage regeneration market
Growth opportunities and latent adjacency in Cartilage Repair Market